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Lawrence Charnas Selected Research

domagrozumab

8/2022Quantitative magnetic resonance imaging measures as biomarkers of disease progression in boys with Duchenne muscular dystrophy: a phase 2 trial of domagrozumab.
2/2021Corrigendum to "Randomized phase 2 trial and open-label extension of domagrozumab in Duchenne muscular dystrophy" [Neuromuscular Disorders, Vol. 30 (6) 2020, 492-502].
1/2020Randomized phase 2 trial and open-label extension of domagrozumab in Duchenne muscular dystrophy.

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Lawrence Charnas Research Topics

Disease

5Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
08/2022 - 01/2020
1Disease Progression
08/2022
1Muscular Dystrophies (Muscular Dystrophy)
01/2021
1Heart Diseases (Heart Disease)
01/2021
1Cardiomyopathies (Cardiomyopathy)
01/2021
1Cardiovascular Diseases (Cardiovascular Disease)
12/2013
1Hyperlipoproteinemia Type III (Broad Beta Disease)
12/2013
1Myocardial Infarction
12/2013
1Cholesterol Ester Storage Disease
12/2013
1Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)
09/2011
1Homocystinuria
07/2008
1Methylenetetrahydrofolate reductase deficiency
07/2008
1Metabolic Diseases (Metabolic Disease)
10/2007
1Hyperalgesia
02/2007
1alpha-Mannosidosis
05/2004

Drug/Important Bio-Agent (IBA)

3domagrozumabIBA
08/2022 - 01/2020
2Biomarkers (Surrogate Marker)IBA
08/2022 - 10/2021
2TroponinIBA
10/2021 - 01/2021
1DystrophinIBA
08/2022
1Proteins (Proteins, Gene)FDA Link
08/2022
1CreatineIBA
10/2021
1Glutamate DehydrogenaseIBA
10/2021
1SilverIBA
01/2021
1LDL CholesterolIBA
12/2013
1CholesterolIBA
12/2013
1LipidsIBA
12/2013
1Fatty Acids (Saturated Fatty Acids)IBA
09/2011
1HomocysteineIBA
07/2008
1Folic Acid (Vitamin M)FDA LinkGeneric
07/2008
1Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA
07/2008
1Gabapentin (Neurontin)FDA LinkGeneric
02/2007

Therapy/Procedure

1Cell- and Tissue-Based Therapy (Cell Therapy)
10/2007
1Hematopoietic Stem Cell Transplantation
05/2004